Calcium May Decrease Risk of Age-Related Macular Degeneration

calcium reduce macular degeneration

A greater intake of calcium was linked to a lower risk of progression to late, age-related macular degeneration (AMD), according to a study reported in JAMA Ophthalmology.*

From 1992 to 2001, the Age-Related Eye Disease Study (AREDS) evaluated the effects of nutritional supplements on cataracts and AMD.

The study included 4,751 men and women, who were followed until 2005. Among those whose intake of calcium from food was among the top 20% of participants, there was a 27% lower risk of developing late AMD in comparison with subjects whose intake was among the lowest 20%. When calcium supplementation was evaluated, participants whose intake was among the top one-third had a 30% lower risk of developing neovascularization than those who did not use calcium supplements.

Editor’s Note: The authors found that, “Women in the highest tertile of calcium supplementation had a lower risk of progression to neovascular AMD…compared with those who did not take calcium supplements. Similar findings were found in men for dietary calcium. Too few men took calcium supplements to allow for analyses.”


*JAMA Ophthalmol. 2019 May 1;137(5):543-550.

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